Calico Biosystems

Predicting life changing drugs
for patients with cancer

Harness the power of multi-omics on intact tumors to identify promising drug candidates and revolutionize cancer treatment.

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Oncology Drug Development

Accelerating Oncology Drug Development with Calico Biosystems NAM Platform

Oncology Drug Development NAM platform

Our Advantages

Calico Biosystems is a disruptive NAM* oncology platform grounded in patient tumor biology setting a new standard for oncology drug development.

Calico tests drug efficacy directly on native patient tumors with unmatched precision before initiation of clinical studies.

Calico’s proprietary stack combines global patient tumor sourcing via cryopreservation with AI‑driven efficacy scoring to deliver unmatched efficacy predictive power.

*NAM (New Approach Methodologies)

Validated across 9 studies, 7 indications, and 300+ patient tumors, Calico delivers proven impact in de‑risking drug development, accelerating and improving clinical translation.

Positioned at the forefront of FDA‑driven NAM adoption, Calico benefits from a powerful regulatory tailwind.

Built on deep founder expertise in oncology and clinical translation, Calico combines scientific excellence with execution at scale.

YOUR BENEFITS

Support

HOW DOES CALICO BIOSYSTEMS SUPPORT DRUG DEVELOPERS (Pharma & Biotechs

  • Patient tumor validation (no cell line or organoid artifacts) delivering direct, clinically relevant efficacy data.

  • Indication prioritization and combination therapy insights to optimize clinical entry

  • Experimental biomarkers to enrich clinical cohorts with treatment responders

  • Strengthen your IND dossier with predictive NAM‑based data

  • Strengthen your Series A narrative with differentiated data and clinical insights

Partner

STRATEGIC PARTNERS & ECOSYSTEM NETWORK

Calico Biosystems is the next‑generation preclinical and early clinical NAM platform, delivering capabilities no CRO currently offers.

Riding the wave of FDA-driven NAM adoption, Calico Biosystems has entered strategic partnerships with CROs and AI innovators to scale globally.

Looking to improve oncology trial success rates with a human biology truth layer ? Seeking a partner to scalable revenue stream with zero disruption to existing operations?  Let’s talk.

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We’d love to hear from you!

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